Dunaliella
salina is genus most important species for β-carotene production. Several
investigations have demonstrated that D. salina produces more than 10% of its
dry mass. β-carotene is an important pro-vitamin A source and can also act as a
lipid radical scavenger and as a singlet oxygen quencher.
Vitamin A
Deficiency (VAD) has been related with cancer, for this reason synthetic and
natural β-carotene has been used for prevention and treatment of the disease.
Synthetic β-carotene is cheaper
than natural molecule but only contains all-trans-β-carotene (ATβC), while
9-cis-β-carotene (9CβC) and ATβC are both produce by D. salina.
Meta-analysis
of controlled trials using high levels of synthetic β-carotene supplementation
in smoker’s individuals, mention that instead to prevent and control lung
cancer, treatment increases risk and percentage of positive cases. Results
obtained in cancer cell lines and animal models using β-carotene from
Dunaliella, prevented and controlled diseases proliferation. In this work,
effects of synthetic and natural β-carotene from D.
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