Adjuvants are
defined as any compound or complex molecular or supramolecular assembly that
can increase the immune response when is administered in formulation with an
antigen.
In this way,
adjuvants have the ability of act as immune enhancers, this promotes
early innate immune responses which increase the effectiveness enabling antigen
recognition.
This topic is an
important research field due to immunization with purified protein antigens
typically results in the induction of a modest antibody response with little or
no T-cell response, so required multiple immunizations to obtain an adequate
protective response.
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